Raising Health - Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection 封面

Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection

本集简介

Out-of-Pocket is a healthcare education company founded by Nikhil Krishnan that helps people understand how healthcare works and how to navigate it in practice. In this episode, a16z investing partner Jay Rughani and Nikhil discuss why health insurance is losing its role as the default way people access care. They explain how rising costs are pushing more consumers to pay out of pocket for diagnostics, preventive care, and navigation. The conversation also looks at what this shift means for startups, AI-powered tools, regulation, and access as healthcare continues to move beyond insurance. Resources: Follow Jay Rughani on X: https://twitter.com/JayRughani Follow Nikhil Krishnan on X: https://twitter.com/nikillinit Read Out of Pocket’s 2026 Predictions: https://www.outofpocket.health/p/out-of-pockets-2026-predictions Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://x.com/a16z Find a16z on LinkedIn: https://www.linkedin.com/company/a16z Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYX Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711 Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details, please see http://a16z.com/disclosures Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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Speaker 0

如果你去我们那个健康保险的子版块看看,现在最常见的问题就是:嘿。

If you go on the, like, our health insurance subreddit, extremely common question now of just, hey.

Speaker 0

我是不是干脆别买健康保险了?

If should I just not get health insurance at all?

Speaker 0

这些就是我的保费。

These are my premiums.

Speaker 0

我目前付的就是这个价钱。

This is kind of what I'm paying.

Speaker 0

我需要的药大概是这种,诸如此类的。

This is kind of the drug I need or blah blah blah.

Speaker 0

对很多人来说,答案其实很可能是否定的。

And for a lot of people, that answer is actually probably no.

Speaker 1

我们美国现在的医疗体系,供给严重不足。

The health care system that we have today in The US is drastically supply constrained.

Speaker 1

美国有两千三百万人在医疗行业工作,可还是排队排到天荒地老,一亿多人连个家庭医生都挂不上,能挂上的话,等四十天以上都是常态。

23,000,000 Americans work in health care, yet we've got long wait times, 100,000,000 people plus don't have access to a primary care doc, forty day plus wait times to see a doc if you can.

Speaker 0

现有的医疗体系,他们真想给每个人制定统一的治疗标准,对吧?搞一套通用指南,让医疗水平整体达到中等水准。

The existing healthcare system, they really want to create standardized care for people, right, and standardized guidelines to make medicine good at the median level for everybody.

Speaker 0

对吧?

Right?

Speaker 0

但与此同时,大家又希望在医疗决策上能有更多的自主权。

But at the same time, people want more agency in their health care in some capacity.

Speaker 0

没人愿意被人一句话打发:嘿。

No one wants to be told like, hey.

Speaker 0

你先等着看吧。

Just wait and see.

Speaker 2

如果美国人开始绕开传统医疗体系,自己重建一套医疗模式,会怎么样?

What happens when Americans start rebuilding health care outside the traditional system?

Speaker 2

他们不是拒绝医疗,而是现在的就医方式、定价和服务流程,早就跟人们实际的使用习惯脱节了。

Not because they reject health care, but because the way care is accessed, priced, and delivered no longer matches how people actually use it.

Speaker 2

多年来,美国……

For years, The U.

Speaker 2

S.

S.

Speaker 2

美国的医疗体系一直围绕保险构建。

Health care system has been organized around insurance.

Speaker 2

《平价医疗法案》扩大了覆盖范围,降低了无保险人口比例,一度让整个系统看起来趋于稳定。

The Affordable Care Act expanded coverage and brought the uninsured rate down, and for a time, the system appeared to be stabilizing.

Speaker 2

但保费上涨、免赔额高、就医难,导致很多人花更多钱,却用得更少。

Rising premiums, high deductibles, and limited access have left many consumers paying more while using care less.

Speaker 2

因此,人们的行为正在改变。

In response, behavior is changing.

Speaker 2

有些人干脆彻底退出了保险体系。

Some people are opting out of insurance entirely.

Speaker 2

另一些人虽然保留保险,却越来越多地自费购买诊断服务、预防性护理、会员方案和数字工具——这些服务能提供更快、更清晰、更有掌控感的体验。

Others keep coverage but increasingly pay out of pocket for diagnostics, preventative care, memberships, and digital tools that offer speed, clarity, and control.

Speaker 2

医疗正在转向主动筛查、持续监测和个性化引导,而且常常发生在传统诊所之外。

Care is moving towards proactive screening, monitoring, and navigation, often outside traditional clinical settings.

Speaker 2

这种转变不只是消费者行为的变化,它正在重塑整个医疗体系的结构。

This shift is not just about consumer it's reshaping the health care stack itself.

Speaker 2

一批新公司正在崛起,帮助人们寻找医疗服务、比价、解读检测结果,以及长期管理健康。

New companies are emerging to help people find care, price services, interpret results, and manage health over time.

Speaker 2

人工智能已经开始在分诊、导航、诊断和临床流程中发挥作用,尽管监管和报销机制还远远跟不上消费者的需求。

AI is beginning to play a role in triage, navigation, diagnostics, and clinical workflows, even as regulation and reimbursement continue to lag behind consumer demand.

Speaker 2

与此同时,一些根本性的矛盾依然悬而未决。

At the same time, core tensions remain unresolved.

Speaker 2

当医疗服务脱离保险体系后,急诊需求并不会消失。

Emergencies don't disappear when care moves outside insurance.

Speaker 2

成本只是在系统内部重新分配了。

Costs shift across system.

Speaker 2

随着医疗体系分裂成并行的多条路径,关于可及性、公平性和可持续性的问题越来越没法回避。

Questions around access, equity, and sustainability become harder to ignore as health care fragments into parallel pathways.

Speaker 2

今天,我们来看看消费者行为、技术和经济力量是如何交汇在一起,重新塑造医疗格局的。

Today, we examine how consumer behavior, technology, and economics are converging to reconfigure U.

Speaker 2

S.

S.

Speaker 2

医疗健康。

Health care.

Speaker 2

我们聊聊为什么保险模式正在变化,自费医疗和主动式护理如何兴起,创业者们正在做出哪些应对,以及这场转型对医疗体系长期结构意味着什么。

We discuss why insurance is happening, how cash pay and proactive care are expanding, what founders are building in response, and what this transition could mean for the long term structure of care.

Speaker 2

a16z健康与生物领域合伙人杰·鲁加尼与Out-of-Pocket创始人尼哈尔·克里希南对话,探讨医疗健康如何在传统体系之外一点一点被重新构建。

A16z Health and Bio partner Jay Rughani sits down with Nikhil Krishnan, founder of Out-of-Pocket, to explore how health care is being rebuilt piece by piece outside the traditional system.

Speaker 1

尼哈尔,现在到底发生了什么?

Nikhil, what's happening?

Speaker 1

老兄,最近咋样?

What's up, man?

Speaker 1

2026年,医疗健康领域开局势头真猛。

So health care is off to a hot start in 2026.

Speaker 1

JPMorgan总是让我们先开场

JPMorgan always kicks us off in

Speaker 0

是个好地方。

a good place.

Speaker 0

这个群体

The group

Speaker 1

讨论可热闹了。

chats are buzzing.

Speaker 1

那当然。

Of course.

Speaker 1

OpenAI 刚发布了新的医疗动态。

OpenAI dropped some new health care news.

Speaker 1

他们推出了一款

They got a

Speaker 0

医疗应用。

health app.

Speaker 0

没错。

Totally.

Speaker 0

Anthropic 二号。

Anthropic two.

Speaker 1

Anthropic 二号。

Anthropic two.

Speaker 1

个人健康记录又回来了。

PHRs are back.

Speaker 0

对。

Mhmm.

Speaker 1

特朗普总统今天公布了那个重磅医疗计划。

President Trump announced the great health care plan today.

Speaker 1

我还没看呢。

I haven't read it

Speaker 0

你别问我问题,我真不知道。

yet, so please don't ask me any questions.

Speaker 1

我本来还想考考你呢。

I was gonna quiz you on that.

Speaker 1

犹他州现在让人工智能开药了。

Utah is letting AI prescribe medications.

Speaker 1

当然了。

Of course.

Speaker 1

这事儿真在发生。

That's happening.

Speaker 1

FDA正在放宽对可穿戴设备的监管。

FDA rolling back regulations on wearables.

Speaker 0

临床试验,可穿戴设备。

Trials, wearables.

Speaker 0

我们现在都在用贝叶斯试验了。

We're doing Bayesian trials now.

Speaker 1

啥都干上了。

We're doing it all.

Speaker 1

太疯狂了。

Crazy.

Speaker 1

而且我们有了一个新的食物金字塔。

And we have a new food pyramid.

Speaker 0

没错。

We do.

Speaker 1

有太多话题可以聊了。

So a lot to talk about.

Speaker 0

现在像个向下的箭头。

Like a downward arrow now.

Speaker 1

是的。

Yeah.

Speaker 1

对。

Yeah.

Speaker 1

没错。

Yeah.

Speaker 1

倒过来的倒金字塔,我把你的2025年预测拿去让Claude分析了。

Inverse inverse pyramid, I ran your twenty twenty five predictions through Claude.

Speaker 1

当然。

Of course.

Speaker 1

你得了7.623分,满分10分。

You got a 7.623 out of 10.

Speaker 0

今年才刚开始呢?

Already for the year?

Speaker 0

才过了两周啊。

It's only two weeks.

Speaker 0

不是。

No.

Speaker 1

是去年的。

Last year.

Speaker 1

明白了。

Okay.

Speaker 1

把去年的预测放上来。

Put last year's predictions.

Speaker 1

看起来挺不错的。

It looks pretty good.

Speaker 1

其实挺棒的。

It's really good, actually.

Speaker 1

太具体了,反而没什么意义。

It's too specific to mean anything.

Speaker 1

没错。

Totally.

Speaker 1

但还是挺好的。

But it's good.

Speaker 1

不错啊。

Nice.

Speaker 1

所以听起来效果还不错。

So it sounded good.

Speaker 1

但我还以为你今年更放得开呢。

But I thought you went spicier this year.

Speaker 1

我还以为你2026年的预测更带劲呢。

I thought your 2026 were spicier.

Speaker 1

所以我们今天就来掰扯掰扯。

So we're here to debate them.

Speaker 0

行。

Okay.

Speaker 0

来吧,干一架。

Let's fight.

Speaker 1

现在就开干,然后马上去瞧瞧Calci预测市场的结果。

And let's fight right now, and then we can check the Calci prediction market Straight away.

Speaker 1

对。

Yeah.

Speaker 1

看看谁

See who

Speaker 0

赢了。

won.

Speaker 0

咱们得真金白银地押注才行。

We're put money where listen.

Speaker 0

对。

Yeah.

Speaker 0

除非你真在预测市场里投了钱,不然这根本算不上预测帖。

It's not a predictions post anymore unless you have some Calci, you know, some money in a prediction market.

Speaker 1

你都没真金白银地押上,你折腾啥呢?

You don't have dollars at stake, what are you even doing?

Speaker 1

你到底图个啥?

Why are you even doing it?

Speaker 1

是啊。

Yeah.

Speaker 1

没错。

Exactly.

Speaker 1

行了。

Alright.

Speaker 1

那咱们先聊聊你对医保脱保的预测吧。

So let's start with your prediction on health insurance defection.

Speaker 1

我都把这些预测写在这儿了。

I've got them all up here.

Speaker 1

不错。

Cool.

Speaker 1

对。

Yeah.

Speaker 1

我觉得这能帮我们看清2026年医疗资金的流向,以及之后会怎么变化。

I think that sets the stage on where we think health care dollars will flow in '26 and then will flow into the other.

Speaker 1

你有个预测说,没保险的人数会暴增。

So one of your predictions says that uninsured rates explode.

Speaker 0

没错。

Sure.

Speaker 1

没保险的人数激增,还会引发一系列连锁反应。

The uninsured rate explodes and the second order affects.

Speaker 1

所以人们不愿意再玩医保这个游戏,纷纷退出系统。

So people refuse to play the healthcare insurance game, defecting from the system.

Speaker 1

没保险的人数会飙升到百分之十五,导致急诊室爆满、保费暴涨,现金支付的选择也越来越多。

The rate of uninsured people will skyrocket to fifteen percent leading to consequences like flooded emergency rooms, spiking insurance premiums, and more cash pay options.

Speaker 0

没错。

Exactly.

Speaker 1

现在没保险的人大概占百分之九点五。

So today, the uninsured rate is around nine and a half percent.

Speaker 0

我记得以前是

I had

Speaker 1

得去查一下数据。

to look that up.

Speaker 1

马萨诸塞州低到百分之三,德克萨斯州却高达百分之十八。

As low as three percent in Massachusetts, eighteen percent in Texas.

Speaker 1

真没想到。

Wow.

Speaker 1

我学到了点东西。

I learned something.

Speaker 1

是的。

Yeah.

Speaker 1

2010年2月,也就是《平价医疗法案》出台前, uninsured 率大概在15%左右,其实都快到16%了,跟你之前预测的一样。

In 02/2010 pre Affordable Care Act, it was around fifteen percent, which is 16%, which is where you projected it.

Speaker 1

对。

Mhmm.

Speaker 1

要是真算进步的话,十五年的成果,十二个月就全倒退回去了。

So fifteen years of progress unwinded in twelve months, if you define that as progress.

Speaker 1

没错。

Sure.

Speaker 1

整个国家马上就要变成得克萨斯那样了。

And the whole country is about to look like Texas.

Speaker 1

你给大伙儿详细说说这个。

So lay that one out for us.

Speaker 1

你为什么会这么想?

What made you think that?

Speaker 0

嗯,这其实是多种因素综合起来的。

Well, I mean, it's a combination of things.

Speaker 0

对吧?

Right?

Speaker 0

我写这篇文章的时候,保费补贴还是个热门争议话题。

Like, at the time when I wrote this, obviously, like, premium subsidies were still a big debate.

Speaker 0

当时谁也说不准最后会变成什么样。

So it was unclear where that would sort of shape up.

Speaker 0

就拿我住的纽约来说吧,那里的个人医保市场费用高得离谱。

And, you know, where I live in New York, for example, like we have a extremely high cost insurance individual exchange market.

Speaker 0

对吧?

Right?

Speaker 0

这其中的原因一大堆,咱们就不细说了。

And this for a whole host of reasons that we'd not have get into.

Speaker 0

但当时看起来,个人医保市场的保费会全面暴涨。

But it seemed like the premiums were gonna spike across the board for the individual exchange.

Speaker 0

再加上,小团体保险现在正经历一种怪现象——如果你团队里健康的人多,你就会想:凭什么我要帮那些病得多的人买单?

On top of that, small group insurance is kind of going through this weird thing right now where one, if you have relatively less sick people, you're like, hey, why am I subsidizing the pool of the more sick people?

Speaker 0

不如干脆退出,改用定额筹资这类方式,甚至直接不买保险了,对吧?

Let me like exit it through, you know, things like level funding or any of these other things or even just not offering insurance at all, right?

Speaker 0

现在这确实是个选项,因为劳动力市场现在偏向雇主,只要你员工少于50人,根本不用提供保险。

That's now an option because the labor market has so far tilted to employers that, you know, if you're below 50 people, you don't have to offer insurance either.

Speaker 0

对吧?

Right?

Speaker 0

所以我觉得,很多员工比较健康的雇主都会想:我才不想替那些病得多的人掏钱。

So I think a lot of people with healthier a lot of employers with healthier employees will be like, hey, I don't wanna subsidize these sicker people.

Speaker 0

结果,员工病号多的公司就被困在自己的小池子里了。

And then the employers with more sick employees then are left in their own pool.

Speaker 0

他们的保费直接冲上天,而这些公司也有了同样的选择——干脆不买了。

Those premiums skyrocket, and then the employers in that pool also have the option to not.

Speaker 0

所以说,我觉得很多人最后都会想,我真有必要每年花一万两千多美金买保险吗?还不算那高达的免赔额,我都不记得具体数字了。

So basically, I think there's a lot of reasons why people will eventually just say, hey, should I really be paying, you know, I don't remember what the average premium is, but, you know, 12,000 plus dollars a year for a family with a deductible on top.

Speaker 0

我根本用不上医疗保险。

I don't even use health insurance at all.

Speaker 0

对吧?

Right?

Speaker 0

很明显,大家自己掏的钱越来越多,压力也越来越大。

People are getting squeezed obviously in, you know, their individual wallet share and all that kind of stuff.

Speaker 0

所以他们自然会问自己:值不值?

So they're gonna be asking themselves.

Speaker 0

如果你去看看我们那个健康保险的Reddit子版块,就会发现,这种问题现在太常见了。

And if you go into, like, our health insurance subreddit Mhmm.

Speaker 0

现在大家普遍都在问:我干脆别买医保了行不行?

Extremely common question now of just, hey, you know, should I just not get health insurance at all?

Speaker 0

对吧?

Right?

Speaker 0

这就是我的保费情况

These are my premiums.

Speaker 0

这差不多就是我每年要交的钱

This is kind of what I'm paying.

Speaker 0

这是我需要用的药之类的杂七杂八的开销

This is kind of the drug I need or blah blah blah.

Speaker 0

对很多人来说,最后大概率真的会选择不买保险

And for a lot of people, that answer is actually probably no.

Speaker 0

你仔细琢磨一下就会发现,要是我真的理性算这笔账的话,情况是这样的:

If you think about it for a second, if I were to, like, be really rational about this and I'm thinking, okay.

Speaker 0

我身体一直都不错,今年也没打算要做什么手术或者有什么既定的医疗开销,啥计划都没有。

I'm a relatively healthy person with no expected procedures or medical things this year, like nothing planned.

Speaker 0

要是我真的这么想,再看看我的保费——就说纽约的个人医保市场吧,每个月要交550美元,这还不算完,另外还有五六千美元的免赔额要先自己掏。

If I believe that, then and my premiums, let's say, on the individual market are $5.50 a month, which is like is in New York, plus on top of that, probably like a 5 k, 6 k deductible.

Speaker 0

你说是不是这个理?

Right?

Speaker 0

现在你只要算一算就知道了。

Now suddenly, like, you just do the math.

Speaker 0

对吧?

Right?

Speaker 0

一年保费12乘600,再加个五千的免赔额。

It's 12 times 600 plus a 5 k deductible.

Speaker 0

是啊。

Yeah.

Speaker 0

所以在医保开始报销之前,你就得先掏这么多钱。

So before even anything is covered Yeah.

Speaker 0

到那时候。

At that point.

Speaker 0

对吧?

Right?

Speaker 0

你得先花上一万出头,具体看情况。

You are paying like $10.15 grand depending on Yeah.

Speaker 0

你是谁。

Who you are.

Speaker 0

我其实就是为那些大灾大难买个保障,比如癌症、车祸之类的。

And I'm really just protecting against catastrophes, cancer, car crash, whatever.

Speaker 0

然后呢,这种事情发生的概率其实挺低的。

Then it's like expected probability of that thing happening is like relatively low.

Speaker 0

所以我完全能理解,很多人觉得这钱花得不值。

And so I can totally see for a lot of people saying it's just not worth it for me.

Speaker 1

那咱们先聊聊这事发生的可能性吧,稍微倒回去说一说。

So so let's talk about the likelihood that it's gonna happen, almost just rewind the clock a little bit.

Speaker 1

当然。

Sure.

Speaker 1

这事儿是好事吗?

Is this a good thing?

Speaker 1

你把正反两方面的理由都摆一摆。

Lay out the arguments for both sides.

Speaker 0

我的意思是,缺点其实很明显——很多不太会评估自己风险的人,真出了事可就糟了。

I mean, the con is sort of obvious, which is that I think a lot of people who are not good at guessing their own risk will have something happen to them Mhmm.

Speaker 0

然后就得住院,掏一大笔根本拿不出的钱。

And then end up in a hospital and have to pay a ton of money that they just don't have.

Speaker 0

是啊。

Yeah.

Speaker 0

对吧?

Right?

Speaker 0

所以一个缺点就是,保障少了,万一真出事,就得自己硬扛。

So that's one con is that coverage for people goes down and something bad happens to them and then they have to deal with it.

Speaker 0

对吧?

Right?

Speaker 0

这部分确实挺糟的。

So that part's bad.

Speaker 0

没错。

Yeah.

Speaker 0

而且我觉得,这还取决于你对‘我们到底该不该有医疗保险’这个观点——如果你觉得医疗保险行业本来就该存在,那这种做法会彻底打乱风险池,让整个经济模型变得一团糟,最后可能就只剩下寥寥几家巨头垄断全国市场。

And also, I think that depending on what your view is on should we have health insurance at all, then if you believe that we should have health insurance in health insurance industry Mhmm.

Speaker 0

说白了,最后就剩四五家大公司说了算。

As in general, then this totally fractures, like, the risk pool makes their economics all wonky, blah blah blah, and we'll probably just lead to a handful of payers that do the whole country.

Speaker 1

是的。

Yeah.

Speaker 0

四到五家。

Four or five.

Speaker 0

对吧?

Right?

Speaker 0

你现在就已经能看到这种趋势了。

You're already seeing this right now.

Speaker 0

小保险公司正被大公司疯狂收购,速度特别快。

Smaller health insurance companies getting bought by larger ones, like happening at rapid scale.

Speaker 0

很多蓝盾计划都在不断合并,这类事情到处都在发生。

A lot of the blues plans are consolidating all this kind of stuff.

Speaker 0

是的。

Yeah.

Speaker 0

所以,如果你觉得医疗保险市场应该保持竞争,那这种趋势其实有点违背初衷。

So if you believe we should have a competitive health insurance ecosystem, this kind of defeats that purpose a little bit.

Speaker 0

如果你更支持某种消费者主导的医疗模式——比如给人们一笔钱,让他们自己决定花在哪些他们觉得值得的服务上——那这种模式恰恰是实现这个目标的手段。

The pros of it are if you believe more in a consumer directed health care system in some capacity where, hey, people get money and they should just use that money to pay for services they think are worthwhile to them, then this is sort of the like means to do that.

Speaker 0

对吧?

Right?

Speaker 0

如果人们能更直接地感受到医疗费用,就会更精明地选择服务。

If people feel more healthcare costs directly, they will be better shoppers.

Speaker 0

providers 也会更愿意迎合他们,提升体验,诸如此类。

They will people will try to cater to them more so there's a better experience and all that kind of stuff.

Speaker 0

我觉得很多人其实说得挺对的,第三方支付方正是医疗费用高企的主要原因之一。

So, I mean, I think a lot of people probably, you know, rightfully make the argument that, like, having a third party payer is one of the reasons that costs are so inflated.

Speaker 0

也是为什么当你不是直接付款人时,就医体验会这么差的原因之一。

It's one of the reasons the experience is so bad when you're not the direct customer.

Speaker 0

对吧?

Right?

Speaker 0

是的。

Yeah.

Speaker 0

所以这就是它的利与弊。

So those are the pros and cons of it.

Speaker 1

其实

It really

Speaker 0

关键看情况,没有对错之分。

just depend there's no right and wrong.

Speaker 0

关键看你信奉什么理念,觉得保障应该是什么样子。

It just depends on what your ideology and what coverage should look like is.

Speaker 0

你之前提到的《平价医疗法案》前后的情况。

To your earlier point about Affordable Care Act before and after.

Speaker 0

对吧?

Right?

Speaker 0

比如,其中一个观点是,我们应该在医保市场上建立一个有竞争的保险市场。

Like, one of the beliefs was we should have a competitive health insurance market on the marketplace.

Speaker 1

对。

Yep.

Speaker 0

如果大家都集中在同一个市场里,保险公司就会为了拉客户而竞争,按理说应该像普通市场那样运作,但实际根本没成。

And they will if everyone is on the same marketplace, then they'll compete for people, and it'll function like a normal marketplace for a whole host of reasons that didn't happen.

Speaker 0

所以现在的问题是,我们是该回头重来,还是该加大投入把它修好?

So now the question is, should we go back or should we try and double down and fix it?

Speaker 0

对。

And Yeah.

Speaker 0

还不清楚。

Not clear.

Speaker 1

是啊。

Yeah.

Speaker 1

我觉得,如果我要为自由派的观点做个最强辩护,就是你刚才说的——让市场自由运作,让消费者自己选。

I think I think there's if I were to steelman the libertarian case, which is sort of what you talked about around around the free market, let the consumers kind of choose.

Speaker 1

这其实是在说,有些人会觉得,终于市场开始起作用了,因为产品太差,人们都纷纷离开。

It's basically saying, some people will say, finally the market is working, people are defecting because the product is bad.

Speaker 1

那就让他们走吧。

Let them defect.

Speaker 1

产品自然会改进。

The product will get better.

Speaker 1

如果他们真想留住这些客户,就一定能拉回来;拉不回来,那也没辙。毕竟,大家是用钱包投票的。

If they want those customers, they'll get them back or they won't, And people are voting with their wallets.

Speaker 1

所以,这是其中一方的观点。

So that's one side.

Speaker 1

另一方则是典型的搭便车反驳。

The other side is basically the free rider counter argument.

Speaker 1

我们其实早在2010年2月,医改法案出台前就听过这种说法:有人会说,我不买医保,反正联邦法律明文规定医院必须给我治病。

We kind of heard this back in 02/2010 ahead of the Affordable Care Act was people would go and say, I'm gonna go without in health insurance, knowing that there's a federal law that effectively requires hospitals to take care of them.

Speaker 1

当时大家担心的是,人们会故意避开常规医疗和预防性检查,非得拖到病得不行了才去医院。

And the belief or the worry was that people would go out, would sort of stay away from the traditional care, preventative care, and just wait until things get really bad.

Speaker 1

然后他们最后进医院,费用还是有人买单。

And then they end up in the hospital and it's paid for.

Speaker 1

急诊科是最贵的医疗服务。

ER is the most expensive side of service.

Speaker 1

这是我们能提供的最不划算的医疗方式。

It's the least affordable way we can deliver all kinds of healthcare.

Speaker 1

这推高了所有人的成本,医院得垫钱,而那些没保险的人,实际上让我们不知不觉地为这些无偿医疗埋了单,最终价格全涨上去了。

This increases costs for everyone, hospitals have to pay for it, and the uninsured effectively result in all this uncompensated care that we inadvertently pay for anyways in higher prices.

Speaker 1

所以总的来说,这反而让整个系统运转起来了。

And so overall, it makes the system work.

Speaker 0

是啊。

Sure.

Speaker 1

你觉得这次又会重现搭便车的问题吗?还是这次情况不一样?

You think we're gonna have the free rider problem again with this or does this time feel different?

Speaker 0

我的意思是,这问题估计还是躲不掉,对吧?

I mean, we'll probably still have that problem, right?

Speaker 0

要是没人买保险又生病了,总不能真待在家里硬扛吧。

If people don't have insurance and they get sick, it's not like they're gonna stay home and just ride it out.

Speaker 0

他们肯定得去急诊室,这还用说吗。

They're gonna go to the emergency department, obviously.

Speaker 0

所以这个问题肯定还是躲不掉。

So we're definitely gonna have that.

Speaker 0

我觉得吧,更大的问题其实是——作为一个国家,我们到底该怎么应对医疗上的重大危机?

I do think that, you know, there's like a bigger I think the main ideological question is like, how do you think we as a country should treat catastrophes in healthcare?

Speaker 0

是啊。

Yeah.

Speaker 0

对吧?

Right?

Speaker 0

没错。

Yeah.

Speaker 0

其实很多人说的那些‘用脚投票’、能货比三家的事儿,都是些能提前规划的普通医疗需求。

Like, I think a lot of the stuff that people talk about when they're like, hey, people vote for their feet or wanna go, is shoppable, planable things.

Speaker 0

对吧?

Right?

Speaker 0

这完全说得通。

And that totally makes sense.

Speaker 0

那遇到车祸的人怎么办?

But what do you do with a person who gets in a car crash?

Speaker 0

对吧?

Right?

Speaker 0

人们总说医疗没法货比三家,因为没人会去急诊室比价。

People always make the argument of health care can't be shoppable because people aren't gonna shop for an ED.

Speaker 0

他们不可能在急诊室里挑三拣四。

You know, they're not gonna be on the emergency department shopping for things.

Speaker 0

但这只是特例。

That's but that's a really specific

Speaker 1

是的。

Yeah.

Speaker 0

这种情况。

Case.

Speaker 1

最危急的病例,没错。

The highest acuity Exactly.

Speaker 1

特别严重、特别贵的那种情况。

Really bad expensive stuff.

Speaker 0

是的。

Yeah.

Speaker 0

所以你看其他国家的模式,比如新加坡,这可能是最常见的例子。

And so, you know, if you look at other countries models, for example, right, Singapore maybe is the most common example here.

Speaker 0

对。

Yeah.

Speaker 0

他们试图把这些情况区分开来。

They try to separate those.

Speaker 0

对吧?

Right?

Speaker 0

比如,让那些可购买的服务更偏向现金支付,用他们那种类似HSA的模式。

Like, try to make shoppable services more of a cash pay experience with their you know, their version of what looks like an HSA.

Speaker 0

然后政府负责覆盖那些更严重的医疗开销。

And then the government covers more catastrophic things.

Speaker 0

对吧?

Right?

Speaker 0

比如癌症、住院这些大病开销。

Cancers and inpatient and all this kind of stuff.

Speaker 0

对吧?

Right?

Speaker 0

所以也许我们其实正在加速走向那种模式——你看,现在有这么多现金支付的病人。

So maybe actually this is us speed running to a system like that, where you're like, okay, hey, we got a bunch of cash pay patients.

Speaker 0

他们马上就要涌向那些高危诊疗机构,我们得想个办法把他们接住。

They're also about to show up to these higher acuity places, and we need to figure out a way to cover them.

Speaker 0

得有个方案来应对,不管以什么形式吧。

And we need a scheme to do that, right, in some capacity.

Speaker 1

你也可以这么说,现在社会对健康的期待已经变了。

You could also argue that the goalpost has moved in the culture around health.

Speaker 1

现在整个文化对健康的重视明显提升了。

There's clearly a greater cultural movement around health right now.

Speaker 1

我们有MAHA这样的东西。

We've got MAHA.

Speaker 1

消费者现在更愿意自掏腰包买健康服务。

Consumers are spending more out of pocket for health.

Speaker 1

酒精销量在下滑,保健品销量却在涨,我们——

Alcohol sales are down, supplement sales are We're

Speaker 0

不喝酒了,改打肽了。

not drinking alcohol, we are injecting peptides.

Speaker 1

对,就是这样。

Yeah, exactly.

Speaker 1

peptides 我们待会儿再聊。

We'll get to peptides.

Speaker 1

我们一会儿再说肽。

We'll get to peptides.

Speaker 1

我经常在想,拿现在这种情况跟2009到2010年大家老说的‘搭便车’问题比,这两拨人是不是根本就不是同一群人?

One question that I think a lot about in comparing this to the kind of free rider problem that people talked about a lot in 'nine and 2010 is, are these actually different populations?

Speaker 1

有一拨人特别主动关注健康,收入高,买补剂,自己掏钱打GLP-1,戴Oura环,有Function Health会员,还有Council会员,该做的全做了。

There's one population, which is the proactive health crowd, higher income, they're buying supplements, they're on you know, they're buying GLP-1s out of pocket, they've got an Oura Ring, a function health membership, a council membership, they're doing all the things.

Speaker 1

你身边全是这种人。

All your friends.

Speaker 1

没错,就是这么回事。

Exactly.

Speaker 1

他们跟所有资源都连上了。

They're working with everyone.

Speaker 1

他们本来就有保险,大概率也还会继续有,但同时还自己花钱做一堆额外的健康管理;而另一拨人,就是你提到的、因为失去保障而加速掉队的那群人。

You know, they were already insured and they're likely going to stay insured, but then they're doing these And extra things out of then there's the newly uninsured that you're arguing is sort of accelerating.

Speaker 1

因为补贴没了,大法案又砍了医疗补助,现在他们根本负担不起医疗费用了。

People are losing coverage because subsidies expired, because the big beautiful bill had Medicaid cuts, and now they can't afford it anymore.

Speaker 0

而且

And

Speaker 1

咱们国家在照顾这些人方面,做得并不好。

we're not doing a good job as a country taking care of those people.

Speaker 1

你怎么看这个区别?

What do you think of that distinction?

Speaker 0

我的意思是,说到底,谁都想健康。

I mean, I think at the end of the day, everyone wants to be healthy.

Speaker 0

对吧?

Right?

Speaker 0

只是大家对健康的定义不太一样。

Just the way they define that is a little different.

Speaker 0

对吧?

Right?

Speaker 0

我觉得可能有一部分人,还是高收入群体吧,他们觉得没人管他们,比如没人盯着他们的健康状况。

I think there's a group of people probably again on the higher income scale who are like, I don't feel like I'm being taken care of because there's you know, I'm not being monitored, for example.

Speaker 0

对吧?

Right?

Speaker 0

我觉得现在的医疗系统根本不是按我理想中的方式设计的,所以我干脆自己另找一套更符合我想法的服务,就是更偏向消费型的——我想多享受点医疗服务,这才是正道。

Like, the health care system is sort of not designed for my view of how I think healthcare should And so I am opting out into a separate system that I think more aligns with my view that is more consumption, you know, like in just, I want to be able to consume more healthcare and this is like the way to do it.

Speaker 0

多做点化验,多拍点核磁共振,随便啥都行。

More lab tests, more MRIs, whatever.

Speaker 0

没错。

Right.

Speaker 0

我觉得收入低的人,当然也想健健康康的。

I think if you are lower income, you still obviously wanna be healthy.

Speaker 0

谁不希望健康呢?这目标谁都一样。

No one like that that is still the goal.

Speaker 0

但问题的重心其实不太一样,对吧?

But I think the problem set is a little right?

Speaker 0

比如我就不想为了开个药续个方子,还得专门请假跑医院。

Which is I don't wanna have to take off work to do a doctor's visit for just a prescription refill, for example.

Speaker 0

或者我孩子病了,我就想知道到底怎么回事,对吧?

Or my kid is sick and I just need the answer to what is happening here, right?

Speaker 0

或者我平时吃的药现在涨价了,怎么才能便宜点买到?

Or the drug I normally take costs x amount now, how do I get it for cheaper?

Speaker 0

是吧?

Right?

Speaker 0

我觉得问题可能有点不一样,但最终目标还是一样的。

I don't think that's maybe the problem set is a little different, but the end goal is still the same.

Speaker 0

只是大家对健康、对什么是好医疗的理解,这两类人群的想法肯定不一样。

It's just like the way they think the way people think about health care, about what is good health is just gonna be, you know, different between those groups.

Speaker 0

但不管是谁,大家想要的其实都一样。

But they still want everyone wants the same thing.

Speaker 0

大家都希望医疗更便宜,或者说,特别普遍的一点是,人人都希望价格更透明。

They want healthcare for cheaper or actually, you know, one thing is that I think is very common is everyone wants more transparency on the pricing.

Speaker 0

对吧?

Right?

Speaker 0

就是说,我觉得我得去医院,但一单账单十万美金,我哪付得起啊?

There's like, hey, I think I need to go to the hospital but I can't do a $100,000 bill, right?

Speaker 0

我想做个化验,可没人告诉我去醫院做要花多少钱,对吧?

Or I wanna get lab tests done but like no one is telling me how much it costs if I like go to the hospital to do that, right?

Speaker 0

所以大家都想要价格透明,我觉得现金支付市场在这两端都在努力满足这个需求。

So everyone wants price transparency and I think the cash pay market on both ends try to serve that.

Speaker 1

你觉得在这两大群体之间,会不会冒出第三种类型?

You think there's gonna be a third category that emerges here between those two camps?

Speaker 1

比如中产阶层的人,其实买得起保险,但选择不买——可能是因为公司太小不给上保险,或者自己创业,本来可以在医保交易所买,但没买。

As an example, a member of the middle class who could afford insurance but chooses to go uninsured, they probably would have got health They either work for a very small employer that maybe doesn't offer healthcare or they work for themselves and they would have bought on the exchange as an example.

Speaker 1

他们就赌一把,用现金支付+主动管理健康,冒点风险。

And they're gonna bet on cash pay plus proactive health and risk it.

Speaker 1

因为这其实是一种介于两者之间的第三种模式。

Because that would be a third category in between these two.

Speaker 1

你觉得没保险的人数增长,就是从这儿来的吗?

Do you think that's where the growth in uninsured comes from?

Speaker 0

你知道医疗互助组织是怎么回事吗?

So you know what health sharing ministry is on?

Speaker 0

这个嘛,就是那种……

So this is like the

Speaker 1

先说一下,这挺有意思的。

first- Explains this interesting.

Speaker 0

对不太了解的人解释一下,这跟普通医保不一样——普通医保是你每月交保费,钱放进一个池子里,出了事再从池子里拿钱赔你。

Okay, so for people who don't know what this is, it's basically instead of health insurance as you know it, which is, a, I pay premiums and into this pool and then when things happen, they pay out to other people.

Speaker 0

但在医疗互助组织里,你其实是先往一个账户里存钱,看起来像保费,但严格来说不算保费。

In health sharing ministries, the, you know, high level is you preload a wallet essentially with something that looks like premiums, but it's technically not premiums.

Speaker 0

然后当其他成员有医院账单时,大家就从这个账户里凑钱帮他们付账。

And then when other members have a hospital bill that happens, people contribute from that wallet to pay for the hospital bills.

Speaker 0

这有点像医疗领域的众筹,不过只在一群事先审核过的成员之间进行。

So it's a little bit more of a crowd, almost like crowdfunding for healthcare, but amongst a specific pool of people that are essentially pre vetted before they come.

Speaker 0

这种模式通常便宜很多,原因有很多。

So those are typically much cheaper and this for a bunch of reasons.

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Speaker 0

对吧?

Right?

Speaker 0

第一,他们能做以前医保计划能做的事——比如因为已有病症拒保。

One, they can do things that plans used to be able to do pre Affordable Care Act, deny people based on preexisting conditions.

Speaker 0

对吧?

Right?

Speaker 0

所以他们的风险群体整体上好得多,对吧?

So their risk pool is much better, right, as a whole.

Speaker 0

而且也不用像保险公司那样,被要求保留大量资本金以防出事。

And also, don't have the same regulatory requirements of, hey, we have to have a bunch of capital on your book so you don't go and solve it.

Speaker 0

这种情况是存在的,对吧?

This happens, right?

Speaker 0

所以你们的合规要求更低,合规成本自然也更低。

So your regulatory pay your regulatory requirements are lower, so your cost for compliance and all that is lower too.

Speaker 0

这其实是个挺有意思的模式:你要是住院了,收到账单,拿给大伙儿看,然后大家就一起凑钱帮你付。

But it's like an interesting model where you're like, hey, if I go to the hospital, I get a bill and I show this to the people and then they all contribute to it.

Speaker 0

但问题是,你得指望大家真愿意掏钱,不然就玩完了。

But the downside is you gotta better you better hope that people are actually down and will pay for it.

Speaker 0

我觉得这产品对某些人来说还挺特别的——我说‘特别’,不是说认同它的理念,只是觉得……

And I do think it's an interesting product for people who are and when I say interesting, I don't mean, like, ideologically agree with it, but I do just think

Speaker 1

它其实是在推荐这个东西。

it's recommending it.

Speaker 0

我不是在推荐它,但我认为它多少碰到了一个中间地带:你看,

I'm not recommending it, but I do think this is it probably addresses this middle ground a little bit where it's like, hey.

Speaker 0

我现在的医保太差了,该报的都不报,还贵得要命。

Like, the health insurance I currently have sucks, and it's not covering the things I wanted to cover anyway, and it's really expensive.

Speaker 0

我早就赌上一把了,反正也不知道保险到底会不会赔我,很多人都是这样。

I'm already gambling on whether or not the insurance is gonna cover me or not, which was the case for a lot of people.

Speaker 0

他们说:‘我买了这保险,结果去医院一报,人家拒赔。’

They're like, you know, they I'm buying this, so then I go and they deny my claim.

Speaker 0

是啊。

Yeah.

Speaker 0

这种事情本来就有可能发生。

They're already there's a chance of that happening.

Speaker 0

那我还不如试试这个别的办法。

I might as well try this other thing.

Speaker 0

如果我身体好,能参保,保费还能便宜点。

And if I can get in because I'm a healthier person, I pay less for it.

Speaker 0

所以我觉得,很多人在理念上其实也认同这一点。

So I think there's a lot of people that also just ideologically agree with that premise.

Speaker 0

是的。

Yeah.

Speaker 0

这反而给那些处于中间地带的人提供了一种可能。

So that I think becomes sort of potential for people in that middle Zone.

Speaker 0

对。

Yeah.

Speaker 0

但现在的体系根本没为这种情况做好准备,因为很多人还得自己去挑医疗服务,对吧。

But the infrastructure is not built for that because a lot of those people, again, have to go and shop for their own care Yeah.

Speaker 0

还得去跟医院谈价,这类事儿,有些医疗分摊组织还真提供帮忙谈价的服务。

Negotiate the bill, all this kind of stuff, which and some of these health sharing ministries offer services to help you negotiate and all this kind of stuff.

Speaker 0

但这本质上是一种完全不同的医疗消费模式。

But it's just also a very different model of health care consumption.

Speaker 0

这里头其实还涉及一种文化转变——人们得主动去跟医生谈价格,而且愿意这么做。

Like it's there's also some cultural change that happens here where people have to go and are willing to, like, negotiate prices with providers.

Speaker 0

这事儿现在还不常见。

That is not a normalized thing.

Speaker 0

也许以后会变得普遍起来,那……

Maybe that becomes more normal, That

Speaker 1

这说得通。

makes sense.

Speaker 1

挺有意思的。

It's interesting.

Speaker 1

你会报名参加一个

Would you sign up for a

Speaker 0

医疗共享事工吗?

health sharing ministry?

Speaker 0

我啊……

I

Speaker 1

我不太确定自己会不会加入。

don't know if I would.

Speaker 1

其实我不希望咱们的医疗体系分裂成两个完全不同的群体。

Actually, so I don't want our health care system to splinter into two groups.

Speaker 1

就是一部分人有能力放弃常规医保,直接自费看病,靠自己这套方式打理医疗开支,剩下的人却只能困在现有的医疗体系里,只能靠慈善救助,说白了就是自己掏腰包填医疗系统的窟窿。

One group that can afford to defect from health insurance, go cash pay, and run their own healthcare stack that way, and then folks that are effectively cycling through our existing healthcare system, relying on charity care effectively out of pocket for the health system to pay for it.

Speaker 1

我今年花了点时间研究不同国家的医疗市场。

I spent a little bit of time this year studying different healthcare markets.

Speaker 1

比如墨西哥就在一定程度上是这种情况,当然两者不能完全对标,但墨西哥确实是富人有一套专属医疗体系,穷人又是另一套。

Mexico as an example has that to some extent, it's not a perfect parallel, there's one system for the rich and another system for the poor.

Speaker 1

这就是我最担心会出现的坏局面了。

So that would be the that would be the downside case that I would worry about here.

Speaker 1

当然。

Sure.

Speaker 0

其实呢,我觉得美国医疗体系的核心问题就是风险池太多了,对吧?

There is also I mean, so for one, I think the core problem with US healthcare is just like we have too many risk pools, right?

Speaker 0

你只能二选一。

You kind of have to choose one or the other.

Speaker 0

总想着搞个折中,比如一部分自费,一部分用保险。

Like having this, hey, maybe we're a little cash pay, Maybe we're a little bit pay a little bit insurance.

Speaker 0

有些人靠雇主提供的保险。

Some people are in employer insurance.

Speaker 0

有些人是医保(联邦医疗保险)。

Oh, some people are Medicare.

Speaker 0

这才是真正的问题所在。

That's kind of the core problem.

Speaker 0

对吧?

Right?

Speaker 0

我们得选其中一个方向。

We have to move to one or the other.

Speaker 0

对吧?

Right?

Speaker 0

比如奥巴马医改,本来的想法是把所有人都纳入个人医保市场,让大家统一在这儿买保险。

So, you know, for the ACA, the idea was we'll move everyone theoretically to this individual exchange, and everyone will buy from that.

Speaker 0

至少大伙儿都在同一个风险池里了。

That's at least they're all in the risk pool.

Speaker 0

对吧?

Right?

Speaker 0

那样就更像德国了。

And that looks more like Germany.

Speaker 0

是的。

Yeah.

Speaker 0

你也可以完全走自费路线,所有人都自掏腰包,就专注这一块。

You could also do totally cash pay, right, where it's like everyone is cash pay and you're just focused on that.

Speaker 0

这看起来更像印度,或者像新加坡那样,把门诊和住院分开来搞。

That looks maybe more like an India, for example, or like a Singapore if you're doing it through out splitting outpatient and inpatient out.

Speaker 0

对吧?

Right?

Speaker 0

但你必须二选一。

But you have to pick one or the other.

Speaker 0

像美国这种半吊子的中间路线——

Like, this in between Americans

Speaker 1

就是喜欢选择多。

love choice.

Speaker 1

我们就是爱选择多。

We love choice.

Speaker 1

谁都想要有多个选项。

Everyone wants to have an option.

Speaker 1

我们愿意为选择多付钱。

We pay for the choice.

Speaker 0

选择反而是最糟的方式。

Choice is like the worst way.

Speaker 0

现在根本是在最差的选项里挑一个。

It's choosing between the worst options now.

Speaker 0

但反过来,还有一个意识形态的问题:你真觉得人应该能花钱买更好的医疗服务吗?

But also on the flip side, there's, again, like, the ideological question of do you believe that you should be able to pay for better care?

Speaker 0

是的。

Yeah.

Speaker 0

对吧?

Right?

Speaker 0

我觉得这个问题让很多人特别不舒服,因为他们内心根本没法接受:‘人居然真能花钱请更好的医生?’

And I think a lot it may that question makes a lot of people really uncomfortable because it's like they cannot reconcile internally that, oh, people should be able to pay for better doctors.

Speaker 0

如果你不认同这点,也没关系,但结果就是,一旦所有人都只能用同一个医疗系统,私下总会冒出另一个平行系统,让人绕开它——不管怎样都能买到更好的服务。

Well, if you don't want that, and that's fine, what ends up happening is that if everyone gets access to one care system, then there will emerge a parallel system that allows them to do that no matter what, right?

Speaker 0

因为有人会说:‘我出钱,直接找最好的医生,现金支付’,哪怕官方系统已经存在,这些好医生也会溜走。

Because they'll be they'll say, hey, I'll pay for the best doctors, cash, even if there is an existing one, and those doctors will exit, right?

Speaker 0

这其实就是现在所谓的会员制医疗、私人医疗在发生的事,对吧?

And that's kind of what's happening today with a concierge medicine and all this kind of stuff, right?

Speaker 0

大家都说,希望全科医生能照顾到每个人。

Everyone's, hey, we want primary care physicians to be able to see everyone.

Speaker 0

这不就是所谓的平等主义嘛,诸如此类的说法。

It's like the great equalizer, all this kind of stuff.

Speaker 0

可突然间,有人就说:我愿意花大价钱,就为让你别管别人,专心照顾我。

And then suddenly people are like, I will pay a lot of money for you to just not do that and then come just take care of me.

Speaker 0

对吧?

Right?

Speaker 0

没错。

Yeah.

Speaker 0

事实上,这种事早就已经在发生了。

The reality is that's kind of already happening.

Speaker 0

我想不到任何一个国家,哪怕是像英国这样的全民医疗体系,能完全避免这种情况。

I can't think of a single system even in socialized medicine countries like The UK.

Speaker 0

人们还是会买私人保险,就是为了能早点看上医生,诸如此类的事。

People still get private insurance and to to see see docs with lower wait times, all this kind of stuff.

Speaker 0

我觉得,根本不可能有个系统能完全杜绝花钱买更好医疗服务的可能性。

Like, I don't think it's possible to actually have a system where you can't pay for better care.

Speaker 0

这事儿就是会自然发生。

It just happens.

Speaker 0

只要不 outright 禁止,它迟早会形成一个市场,不管你怎么搞。

It'll just emerge as an economy no matter what unless you unless you ban it, right?

Speaker 0

当然,你也可以禁,但那也会带来一堆别的问题。

Which like you can do, but that has its own sort of downsides to it too.

Speaker 0

比如加拿大,就是个没法搞双轨制的例子。

Like Canada, for example, is an example of not being able to parallel system.

Speaker 0

结果就出问题了,有人会说:‘我要是得了复杂病,干脆直接去美国看。’

And that has its own issues where people are like, hey, if I have a complex care thing, I'm gonna come to The US.

Speaker 0

所以我也说不准,但我觉得咱们得接受一个现实:不管你怎么做,最后大概率还是会变成——有人愿意花钱买更好的医疗服务。

So I don't know, like, we gotta get comfortable with the idea that I think you have to you will probably no matter what end up with a system where people pay for better care.

Speaker 0

你可以用特别绕的方式做,也可以直接明明白白地做,或者干脆尊重大家愿意为哪些服务多花钱的选择。比如在印度这样的国家,人们就可以花钱享受更好的医疗条件,对吧?

You can either do that in a really convoluted way or just do that in a straightforward way or do that in a way where you're more comfortable with what they choose to pay for, So for example, in countries like India and stuff, can pay for better amenities, right?

Speaker 0

就是 nicer 的待遇啊,各种好东西。

Like the nice rewards and all this kind of stuff.

Speaker 0

这么说,可能反而更容易让人接受。

Like, maybe that's a more palatable way to do that, basically.

Speaker 1

是的。

Yeah.

Speaker 1

对,这挺有意思的。

Yeah, it's interesting.

Speaker 1

如果真这么发展下去,比例到底是15%、18%还是12%还不确定,但从Reddit上的讨论来看——这可是我的亲身观察。

Where is the so if this plays out and TBD, if it's 15% or 18% or 12%, but it's clear that per the Reddit threads, That's which is my truth.

Speaker 1

这确实是我的看法。

That's my truth.

Speaker 1

人都在往外面跑。

People are defecting.

Speaker 1

是的。

Yeah.

Speaker 1

这对初创公司会有什么连锁影响?

What are the ripple effects for startups?

Speaker 1

如果你打算创业,显然那些主动健康管理类的初创公司会有机会,因为大家更愿意自费消费,但还有别的吗?

If you're trying to start something, obviously the proactive health startups have an opportunity here, more cash pay spend, but what else?

Speaker 0

对,我觉得针对这群人,医疗导航的方式也会完全不同,确实如此。

Yeah, I think also just like care navigation looks very different for this group of people, Totally.

Speaker 0

你得认真想想,你这事到底有多严重,值不值得花大价钱去看医生,特别是你自己掏钱的时候,对吧?

I think you have to really think about, is this thing I'm doing serious enough that I need to go see a higher cost medical practitioner if you're paying out of pocket, right?

Speaker 0

这种初步筛选的步骤,跟以前完全不一样了。

That triaging step is really different.

Speaker 0

所以我觉得,帮人们搞清楚‘我该去哪儿看这个病’特别重要。

So I do think that helping people figure out like, hey, where do I go for this?

Speaker 0

还有,这事儿到底严不严重,非得跑一趟不可吗?

And is this actually serious enough that I need to go?

Speaker 0

这本质上就变成了一种完全不同的产品类型。

Becomes a whole separate type of product to build basically.

Speaker 0

跟有保险的人不一样,你得帮他们一步步搞定保险、医疗网络、报销这些事儿。

Compared to someone who have insurance, you're really navigating them through their insurance, directory, coverage, whatever it is.

Speaker 0

所以我觉得这完全是两码事。

So I think that looks very different.

Speaker 0

我觉得另一个连锁反应是,会冒出一堆人想以超低价格提供医疗服务。

I think another ripple effect too is there's gonna be, I think, lot of people that try to deliver care at, like, hyper lower costs.

Speaker 0

对吧?

Right?

Speaker 0

比如那个Doctronic,犹他州的那个试点项目,我记得他们开药续方只要四美元一次。

So the Doctronic, you know, the pilot in Utah is a good example where I I remember correctly, they're doing prescription refills at $4 a pop.

Speaker 1

而不是一块五?

Instead of $1.50?

Speaker 0

对。

Yes.

Speaker 0

是的。

Yeah.

Speaker 0

这其实还挺便宜的。

Which, you know, that is actually pretty that is relatively affordable.

Speaker 0

你需要续个处方。

You need a prescription refill.

Speaker 0

对。

Yeah.

Speaker 0

这样一条路就能解决,不用再专门跑一趟看医生。

That is like one route can go rather than having to do a totally net new visit to the doctor.

Speaker 0

对吧?

Right?

Speaker 0

我觉得这类服务会越来越多。

So I do think you'll see more of this, hey.

Speaker 0

我们怎么把成本压到极致低?

How do we bring costs, like, an extremely low level?

Speaker 0

很明显,得靠AI、科技,还有这些玩意儿。

Obviously, using AI, using tech, using all this kind of stuff.

Speaker 0

另一个有意思的想法是,能不能跟现有的医疗机构搞点新式的合作,专门针对那些自费看病的病人?

And then the other one, which, like, I think is a little interesting to think about is, you know, can you do some form of novel contracting with the existing providers for when they see people who are coming in as cash pay?

Speaker 0

是的。

Yeah.

Speaker 0

对吧?

Right?

Speaker 0

因为说实话,医疗机构到时候真挺难办的,对吧?

Because the reality is the providers are gonna be in a tough spot, right?

Speaker 0

有人上门自费,结果付不起钱。

Where someone comes in, they have to pay cash, they don't.

Speaker 0

比如说,有人跑急诊做了特别贵的检查,做完就走人,医院去追着要钱,最后根本要不到,对吧?

Like, you know, the if they come into the emergency room, they do some really expensive stuff, people leave, they chase them down for the money and then they don't get it, right?

Speaker 0

所以这种情况下,医疗机构真的挺被动的。

So the provider is in a tough spot when that happens.

Speaker 0

能不能给自费患者提供个特别简单的打包价之类的?比如,嘿,你是自费的,这是我们的价格。

Can you offer really easy like bundled payments or whatever it is to people to be like, hey, you're a cash pay person.

Speaker 0

这是我们的收费标准。

Here's what our rate is.

Speaker 0

直接来就行,别折腾了。

This and come through and get it.

Speaker 0

现在你想查个自费价,得绕一大圈,特别麻烦。

Right now, if you wanted to figure out the cash pay rate for something, you like have to go through a really weird convoluted process to do this.

Speaker 0

你得打电话问,说自己是自费患者,然后还得像砍价一样扯皮。

You call in, you'll say you're a self pay patient, and kinda like haggling.

Speaker 0

我感觉我就像在……

I feel like I'm like the in the in

Speaker 1

印度市场里讨价还价。

an Indian market.

Speaker 1

你懂我意思吧?

You know what I mean?

Speaker 1

我就觉得

I'm just

Speaker 0

咱们这儿来回砍价,搞得跟闹着玩儿似的。

like, we're haggling back and forth, and we're just like, what's up?

Speaker 0

咱们到底要往哪儿走啊?

Where are we gonna be?

Speaker 0

不如干脆给大家整得明明白白的,听好了。

But to maybe just make it really easy for everyone, like, hey.

Speaker 0

这是打包价。

Here's the bundle.

Speaker 0

包含哪些服务都列在这儿了。

Here are the services included.

Speaker 0

你直接来就行。

You can come for this.

Speaker 0

尤其是那些价格高点的项目,比如你没保险又非做不可,我们就给你明码标价,该怎么弄、花多少钱,一清二楚。

And that's gonna especially be true for things like somewhat higher cost procedures and stuff like that, where it's like, if you're uninsured and you do really need that thing, here's how we can do it and here's the cost we'll pay.

Speaker 1

这听起来反而有点像医疗旅游的模式,大家都慕名过来求医。

It looks more like the medical tourism market where people are coming.

Speaker 1

没错,就是这个意思。

Exactly.

Speaker 1

只不过这是本土化的医疗旅游而已。

But it's a local version of that.

Speaker 1

就像有人专门跑到美国来,就想在梅奥诊所接受治疗一样。

But people are coming to The US and they want to get the procedure at Mayo Clinic.

Speaker 1

他们是自费掏钱的。

They're paying out of pocket.

Speaker 1

都没录入我们的系统里。

They're not in our system.

Speaker 1

其实国内也能有这样的服务模式。

There could be a domestic option like that.

Speaker 1

现在就有现成的做法,只不过得把流程简化一下,

It exists today, but just make it easier,

Speaker 0

这事儿现在做起来太难了

It's lower very hard to do

Speaker 1

确实。

that today.

Speaker 0

那这可能算一个方向。

So maybe that's one.

Speaker 1

那咱们跳着聊几个更相关的预测吧。

Okay, so we're going to jump around across some of the predictions just to hit ones that are more relevant.

Speaker 1

如果消费者开始自己主导医疗、更多自费、不再依赖传统体系,那一个趋势就是筛查诊断和居家采样会火起来。

If consumers are defecting, coordinating more of their care and spending more out of pocket, one prediction is that screening diagnostics and at home sample collection becomes the hot area.

Speaker 1

你具体说说这个逻辑。

So lay out the case there.

Speaker 1

你看Lil Jon都在做结肠癌筛查的广告了,大家把粪便样本寄遍全美,简直离谱。

So Lil Jon is doing colon cancer screening commercials, People are shipping their poop around the country, like, just crazy.

Speaker 1

对。

Yeah.

Speaker 0

这事儿只跟医疗健康有关。

It's only for health care.

Speaker 1

根本没关系。

Not even relevant.

Speaker 1

他们就是这么干的。

They're just doing it.

Speaker 1

你知道的,查完邮件记得洗手。

You know, check your wash your hands after you check the mail.

Speaker 1

你详细说说这个。

Lay out that.

Speaker 1

你为啥觉得这会成真?

Why do you think that's gonna happen?

Speaker 0

我的意思是,说清楚点,我觉得不是因为没保险的人变多了才这样。

Well, I mean, to be clear, I don't think it's because the uninsured thing happened.

Speaker 0

对。

Sure.

Speaker 0

但我觉得诊断这个领域特别有意思,却一直被严重忽视。

I but I think that diagnostics is, I feel like, such an interesting area that is, like, very underinvested in.

Speaker 0

对啊。

Yeah.

Speaker 0

你懂的吧?

You know?

Speaker 0

我觉得跟自费医疗有关的一点是,你跟医生和病人聊的时候,会发现大家对这事的看法根本对不上——他们压根没法达成共识。

I think maybe one thing to tie to the uninsured maybe not uninsured, but cash pay rather, is that I think this is one of the areas that a lot of people when you talk to doctors and you talk to patients, this is one thing that I feel like there is a somewhat irreconcilable difference here that they just can't think about.

Speaker 0

就是,大家都希望有人能定期关注自己的健康状况。

Like, the people wanna be monitored in some capacity.

Speaker 0

但很多医生会说:你可以监测啊,但就算监测了,我们也做不了啥。

And a lot of the doctors will be like, well, you could be monitored, but there's not much we can do even if you get monitored.

Speaker 0

对吧?

Right?

Speaker 0

毕竟,监测了也不会改变你的治疗方案。

Like, it's not like your care pathway is going to change doing that.

Speaker 0

但很多人就是希望有人能盯着自己。

But But a lot of people just, like, wanna be monitored.

Speaker 0

对吧?

Right?

Speaker 0

因为他们觉得有人在关心自己,每个环节都被重视,诸如此类的。

Because they feel like someone is looking out for them and they're being considered at all points and blah blah blah.

Speaker 0

所以我觉得大家确实想要这种服务,尤其是自费的客户。

So I think that people want that, and especially in the cash pay.

Speaker 0

你看长寿医学这一块就特别明显。

And you see this with the longevity medicine and all this kind of stuff.

Speaker 0

他们真正想要的,很大程度上就是定期被监测。

Like, a big component of what they want is just like being monitored.

Speaker 0

对吧?

Right?

Speaker 0

就算查不出啥问题,至少咱们确认过一遍了,你说是吧?

Even if it says nothing, it's just at least we checked, you know?

Speaker 0

所以我真的觉得,人们对这种服务的需求特别高。

So I do think that the appetite for that is really high.

Speaker 0

我觉得,随着越来越多采用AI原生的医疗模式,这一点会变得至关重要。

I think as you move to more of these AI native care models, that becomes a really core part.

Speaker 0

对吧?

Right?

Speaker 0

从被动治疗转向主动预防,关键在于用什么数据来告诉你该采取行动了,对吧?

The shift from reactive care to proactive care really has to come from what is the data source that's going to tell you that something has to be done, right?

Speaker 0

我觉得这得靠一些筛查和诊断手段来实现。

And I think that is going to come from some form of screening diagnostics, etcetera.

Speaker 0

我们之前聊过一点AI开药的事儿。

You know, we talked a little bit about the AI, about AI prescribing, for example.

Speaker 0

我觉得比这更进一步、也更有趣的,是AI能自动安排化验或随访,甚至在医生还没来得及看之前就先一步处理了。

I think the next level above that, which will be interesting is like AI ordering things like labs or follow ups that you might need pre the doctor actually needing to look at it.

Speaker 0

对吧?

Right?

Speaker 0

我觉得这也会成为其中一部分。

And I think that is going to be sort of a part of this.

Speaker 0

但总的来说,诊断领域现在也出现了更有趣的市场策略——我们发现有个很大的自费市场,这些人就想被持续监测,同时他们又在等更正规的实验室检测或FDA审批流程。

But in general, like I think diagnostics also are seeing a more interesting go to market strategy too, which is, hey, we basically see a big cash pay market that was just wanting to be monitored while in the meantime, we go through a more legit, you know, lab developed tests or FDA approval route.

Speaker 0

但确实存在一种需求,想用这些新检测手段来监测一些平时不常关注的指标。

But there's this appetite here for these like new tests to just be monitored on different metrics that maybe are not typically monitored.

Speaker 0

而且人们确实有这种意愿。

And they see this appetite from people to do that.

Speaker 0

比如,如果你家族有某种疾病的遗传风险,但又不完全符合临床指南里推荐用药的标准,人们还是会自己想办法去查,而且他们也愿意掏钱。

Like, especially for example, if you have, you know, some family risk of something, right, but you don't quite fit really neatly into guidelines around like that you need to be prescribed this thing, people are gonna find alternative routes to doing that and they have money to do that too.

Speaker 0

他们愿意为此买单。

They're gonna pay for it.

Speaker 0

比如冠状动脉钙化CT扫描,这就是个很好的例子,但偏偏很难做得到。

Coronary, you know, calcium CT scans, like, great example of this, where like, for some reason it's really hard to get that.

Speaker 0

而且,研究证据和临床指南之间,还存在巨大的时间差。

And also, there's still a huge lag between like evidence and sorry, research and then care guidelines.

Speaker 0

对吧?

Right?

Speaker 0

很多时候,从有潜力的新技术到真正成为普遍临床标准,中间能拖上十年以上。

So the lag is like ten plus years in a lot of cases between what's interesting and what actually makes it into, hey, we're doing this for all patients and all this kind of stuff.

Speaker 0

但人们愿意花钱避开这种等待。

But people are willing to pay to to escape that.

Speaker 1

你做过吗?

Have you done it?

Speaker 0

钙扫描?

The calcium scan?

Speaker 0

我没做过,老兄。

I'm not, dude.

Speaker 0

但你要是个三十来岁的南亚人,那你突然就得认真考虑这个问题了。

But I'm like, you know, if you're a 30 year old brown person, like, you're suddenly in a risk category that you have to be thinking about this.

Speaker 1

我就是你刚说的那种典型例子——胆固醇略高,南亚男性,风险因素全占了。

Is it I'm a perfect example of what you just described, which is slightly high on the border cholesterol, South Asian male, so I have risk factors.

Speaker 1

心血管事件。

Cannon event.

Speaker 1

对,就是这样。

Yeah, exactly.

Speaker 1

我医生说,你绝对不需要做钙化CT扫描。

And so my doctor was like, you definitely don't need a calcium CT scan.

Speaker 1

但我就是想知道。

I wanted to know.

Speaker 1

我现在就想找医生问问。

I wanted doctors now.

Speaker 1

开玩笑的。

Just kidding.

Speaker 1

但我还是去做了。

But I did it anyways.

Speaker 1

挺好的。

Cool.

Speaker 1

你查出来结果怎么样?

What'd you find out?

Speaker 1

是零,挺好的。

It was a zero, which is good.

Speaker 1

明白了。

Okay.

Speaker 1

但我就是想弄清楚这个。

But I wanted to know that.

Speaker 1

对。

Yeah.

Speaker 0

知道这个真不错。

That's good to know.

Speaker 0

没错。

Exactly.

Speaker 0

我觉得咱们社会得想明白一件事,现在的医疗系统老想搞一套标准化的治疗方案,对吧?

Like, I I think the tough thing I think the thing that we have to figure out as a society a little bit is that the existing healthcare system really wants to be like, hey, here they really wanna create standardized care for people, right?

Speaker 0

还要搞一套标准化指南,让医疗水平在平均层面上对所有人都有效,对吧?

And standardized guidelines to make medicine also good at the median level for everybody, right?

Speaker 0

但与此同时,大家又希望在医疗决策上能有更多的自主权。

But at the same time, people want more agency in their healthcare in some capacity.

Speaker 0

对吧?

Right?

Speaker 0

没人愿意被告诉:‘你先等等看吧。’

They wanna feel no one wants to be told like, hey, just wait and see.

Speaker 0

他们就是不想听这种话。

They just don't wanna be told that.

Speaker 0

其实有很多低风险的事情,我们可以直接让普通人自己去尝试、去体验。

And there are probably a lot more lower risk things that we can just let people try and do and see.

Speaker 0

我觉得这可能就是为什么现在像休伯曼方案这类东西这么火,还有那些……

I think this is one of the reason for example that protocols are so popular right now, like Huberman protocols and Yeah.

Speaker 0

各种方案都特别受欢迎。

Period of protocols.

Speaker 0

你知道,这些方案的核心其实就是那套老生常谈:吃好、睡好,就是平常听到的那些建议。

You know, the core the core thing of what these protocols are saying is eat well, sleep well, you know, the normal advice you get.

Speaker 0

但

But

Speaker 1

关键是它被包装了。

It's branded.

Speaker 1

没错,是被包装了,但……

Well, it's branded, but

Speaker 0

而且它还给人一种清单感,好像你真得按部就班地去做点什么才行。

also it gives people like what seems like a task list that they should actively be doing to like Yeah.

Speaker 0

让你觉得在好好管理健康,还给你推荐一堆补充剂,让你感觉真的在行动。

Be good at their health and gives them, like, supplements to feel like they're doing something.

Speaker 0

对。

Yeah.

Speaker 0

至于你到底做没做,其实没那么重要,重要的是,这种能自己做主的感觉。

And whether or not they're doing it is sort of irrelevant, but the feeling of having agency in those situations, I think, is actually the important part.

Speaker 0

测试也是同样的道理。

So the same with the testing.

Speaker 0

人们就是想觉得自己能掌控一点局面。

People just wanna feel like they're in control a little bit.

Speaker 0

我觉得这里头其实有个矛盾:一方面,有些病人干脆放任自流,直到症状严重了才去做筛查和诊断,结果反而给医疗系统添了更大压力。

And, you know, I think there's some tension here about, okay, there's clearly a line of, like, where patients are just, like, YOLO ing until screening tests and diagnostics that then end up with, like, more pressure on the health care system.

Speaker 0

比如你做核磁共振,突然发现一堆意外的结节。

Like, you find incident delomas in your MRI.

Speaker 0

然后就得别人来收拾烂摊子,一堆后续问题跟着来。

Now someone else gotta deal with it, all this kind of stuff.

Speaker 0

但我认为,人们还是想要更多主动权——比如当你觉得当前的治疗方案不太靠谱时,至少想做个检查,亲眼看看情况。

But I think people want more agency and getting a test done where you're like, I just don't feel good about what my care plan is today.

Speaker 0

我就想查一查,图个安心。

I just like to see and test.

Speaker 0

不管好坏吧,至少我觉得,这种主动参与,才是未来医疗的走向。

It's just for better or worse, just like I'm be a part of health care going forward.

Speaker 1

我觉得你说得对。

I think that's right.

Speaker 1

而且我觉得这还会引发另一个争论:监管机构到底该允许这些检测和AI应用说什么?

And I think that creates another debate, which is what do regulators allow these tests and AI applications to say?

Speaker 1

对。

Yeah.

Speaker 1

我觉得很多医疗界的人会说,这些检测其实也提供不了什么真正有用或值得关注的信息。

I think a lot of these things, the medical establishment will say, Well, it's not really going to tell you anything that actionable or that interesting.

Speaker 1

但这些东西往往都是从边缘开始的。

But these things start on the fringe.

Speaker 1

我的看法是,我觉得这是件好事。

My take is that I think it's a good thing.

Speaker 0

它们都是从边缘开始,

They start on

Speaker 1

然后慢慢变得主流。

the fringe and then they get more mainstream.

Speaker 1

说实话,我们现在美国的医疗体系,供给严重不足。

I think the reality is that the healthcare system that we have today in The US is drastically supply constrained.

Speaker 1

2300万美国人从事医疗行业,可还是排长队。

So 23,000,000 Americans work in healthcare, yet we've got long wait times.

Speaker 1

这些数据你肯定都听过。

You've heard all the statistics.

Speaker 1

一亿多人找不到全科医生,能约上的话,等四十天以上都是常事,诸如此类。

100,000,000 people plus don't have access to a primary care doc, forty day plus wait times to see a doc if you can, etcetera, etcetera.

Speaker 1

这种种麻烦让人抓狂,需求就像喷泉一样四处乱窜,往各种地方涌去。

And so all that friction is frustrating and the demand exhaust shoots off somewhere and it's shooting off to all these places.

Speaker 0

而且

And

Speaker 1

你说得对,人们都想有自主权,这种自主性自然会往别处跑。

to your point, people want agencies, so that agency is going to go somewhere.

Speaker 1

那它到底往哪儿跑了呢?

And where is it shooting off?

Speaker 1

都跑到大语言模型那儿去了。

It shoots off at LLMs.

Speaker 1

你看到OpenAI那份报告了吗?全球每周有两亿三千万人用ChatGPT问健康问题,每天四千万人次。

So you saw the OpenAI report, two thirty million people around the world using ChatGPT for health related questions each week, 40,000,000 a day.

Speaker 1

太离谱了,真是太离谱了。

It's crazy, It's crazy.

Speaker 1

它都取代医生了。

It's replaced Doctor.

Speaker 1

还有谷歌,还有好多别的东西。

Google and many other things.

Speaker 1

现在好多人都在用主动健康管理工具,比如健康会员服务、Aura和Whoop这些可穿戴设备,随便你说哪个。

The proactive health tools are being adopted by a bunch of people, the health memberships, the wearables like Aura and Whoop, name your thing.

Speaker 1

这不挺合理的吗?

And that makes sense, right?

Speaker 1

大家确实想自己动手管健康,但还是有监管上的障碍,我觉得特别有意思,挺好奇接下来会怎么发展——至少几周前,设备还分两大类。

People want to do stuff with that, but there's still regulatory friction that I find interesting and I'm kind of curious to see how it plays out this which is at least as of a few weeks ago and prior to that, there were two buckets for a device.

Speaker 1

FDA要么说这是个健康类产品,完全不能做任何医疗宣称;要么就认定它是医疗器械,想说什么都行,但得走一遍漫长复杂的审批流程。

FDA either said it's a wellness product and it can't make any medical claims at all, or it's a medical device and you can make all the claims you want, but you've got to go through a long regulatory approval process.

Speaker 0

对,没错。

Yep, yep.

Speaker 1

这明显更有利于大公司,那些老牌医疗科技巨头,初创公司根本玩不转。

That as we know largely favors the incumbents, the big med tech companies, really hard for startups.

Speaker 1

所以相对而言,真正冒出来的设备其实没几个——按理说,本该有更多才对。

So there's not that many on a relative basis devices that have emerged relative to, I think, what could have been possible.

Speaker 1

是啊。

Yeah.

Speaker 1

我就拿我的Oura戒指举个例子。

I'm touching my Oura Ring as an example.

Speaker 1

Oura的Tom,还有他们的投资人,我觉得他之前在《华尔街日报》写了一篇特别棒的评论,说应该搞个第三类分类。

So Tom at Oura, investors there, but I think he wrote this amazing op ed in the Wall Street Journal that basically said there should be a third category.

Speaker 1

这个第三类叫‘数字健康筛查工具’——它不直接给你诊断结果,但能提醒你身体里有几处值得关注的地方,建议你去跟医生聊聊。

And that third category is digital health screeners, which is there's something in between that's not necessarily going to give you direct medical diagnosis, but will show you a couple things that you probably want to know about your body and you might want to talk to your doctor about.

Speaker 1

他在文章里举的例子我觉得挺好的,比如设备能推测出一些高血压的早期信号,提醒你:‘你可能该去跟医生聊聊高血压的事了。’

So the examples that he gave in the article that I thought were good were maybe there's a couple early indicators of high blood pressure that it can infer and tell you to say, Hey, you might want to talk to your doc about hypertension.

Speaker 1

我记得以前看过一个数据,超过百分之四十的成年人已经被诊断出高血压之类的,简直太离谱了,这真是个普遍又难搞的慢性病。

And I think, I can't remember the last statistic, but forty percent plus of adults are diagnosed with hypertension or something So crazy like it's a real chronic condition that's challenging.

Speaker 1

文章里还提到另一个例子:某些睡眠异常可能预示着睡眠呼吸暂停。

The other one that they give in the article is, hey, there's some sleep irregularities that are probably predictive of sleep apnea.

Speaker 1

赶紧去问问医生吧。

Talk to your doctor.

Speaker 0

没错,完全同意。

Yeah, totally.

Speaker 1

对吧?

Right?

Speaker 1

咱们干脆就别管它了。

Like we should just let that go.

Speaker 1

我觉得关键在于,中间其实有个灰色地带——你可以收集大量数据,然后直接丢给大语言模型处理。

And I think that's the There's obviously something in the middle where you could get all this data and then just drop it into your LLM.

Speaker 1

反正大家早就这么做了。

People are doing it anyways.

Speaker 1

我把所有医疗数据都丢进聊天机器人,让它帮我分析。

I drop all my medical data into counsel and pick

Speaker 0

挑一个就行。

the one.

Speaker 1

未来就是这样。

And that's where it's going.

Speaker 1

FDA之前说过一些话,暗示他们打算——

FDA said some things that suggested that they're gonna- They

Speaker 0

明摆着在暗示,心照不宣。

gave the hint, hint, wink, wink.

Speaker 1

是啊,他们确实打算放宽一些可穿戴设备的限制,但这只是开始。

Yeah, they're gonna roll back some of these things on wearables, but wearables is just the start.

Speaker 1

对吧?

Right?

Speaker 1

现在你想想AI医生应用,它们能说啥、能干啥。

Now you get into AI doctor applications and what can they say, what can they do.

Speaker 1

你觉得这事儿咋样?

So what do you think of that?

Speaker 0

我的意思是,归根结底,作为社会,我们该允许病人自己承担多大风险?

I mean, again, I think the question is, as a society, how much risk do you think that patients should be allowed to take on themselves?

Speaker 0

对。

Yeah.

Speaker 0

对吧?

Right?

Speaker 0

比如AI开药这事,可能就是个好例子。

Like, the AI prescribing thing maybe is a good example here.

Speaker 0

对吧?

Right?

Speaker 0

诊断的问题咱们待会儿再聊。

And we'll come back to the diagnostics for a sec.

Speaker 0

但你觉得,一个人应该有权花四块钱,让AI医生直接给你开常见药吗?

But do you think that a person should be able to say, hey, I wanna be able to pay $4 to see the AI doctor who's gonna auto prescribe me via these common meds?

Speaker 0

它有时候可能会出错。

It might get it wrong sometimes.

Speaker 0

一旦出错,受伤害的就是你自己。

And if it does, then it'll harm me.

Speaker 0

你也可以选择多花点钱,找一个更靠谱、准确率更高的医生,这样出错的概率更低,比如开错药之类的风险也更小,随便你怎么说。

Or I can choose to pay a higher amount and see a doctor that maybe has more sort of like higher accuracy or whatever it is and lower chance of me doing risk of having an adverse event or whatever, like getting prescribed the wrong thing, whoever.

Speaker 0

作为个人,你该不该有这个选择权?

Should I be able to make should I be allowed as a person to make that choice?

Speaker 0

你是想选那个便宜但更容易出错的AI医生,还是不选?

That like, want the AI doc that maybe gets it wrong more often, but it's cheaper or not?

Speaker 0

筛查类的可穿戴设备应该也是同样的道理吧?

Probably same thing for screening diagnostic wearables, right?

Speaker 0

它可能从你的数据里发现一些有意思的东西,但同时也会有相当高的假阳性率。

Where it's like, hey, here's the thing that might find some interesting stuff in your data, but also it's gonna have a false positive rate of this much.

Speaker 0

对吧?

Right?

Speaker 0

你可以自己选。

And you can choose that.

Speaker 0

不过这里有个问题,假阳性结果带来的负担,最终会落到去看医生的人、医疗系统或者急诊室头上。

Now I will say the issue here a little bit is that the burden of the false positive rate then falls on the doctor you go and see or the health system or the emergency room.

Speaker 0

所以我觉得这确实是个值得认真考虑的问题:当这种设备大规模普及后,一旦出现假阳性,受影响的可能是数百万人。

So I think that is like a real consideration we have to think about is like when people have these devices at scale, suddenly the risk of when false positive rates happen, it's gonna be millions of people.

Speaker 0

对吧?

Right?

Speaker 0

这可不是闹着玩的。

That's no joke.

Speaker 0

对吧?

Right?

Speaker 0

但与此同时,我觉得我们正在错过大量特别有价值的数据,本该好好利用的。

But also at the same time, I think we're missing a lot of really interesting data that we should be doing more things with.

Speaker 0

比如说,我最近跟不少长期戴连续血糖监测仪的人聊过。

For example, I think, you know, I've been talking to a bunch of people that have been wearing CGMs for a while.

Speaker 0

对。

Mhmm.

Speaker 0

他们当中很多人其实有各种各样的情况,表面上看像糖尿病,但根本不是一回事。

And a lot of them, I think, for example, have different pathologies of what traditionally looks like diabetes.

Speaker 0

比如糖尿病这个说法太笼统了,背后可能藏着好几种完全不同的生理机制,只是都被归到一个名字底下。

Like, for example, I think diabetes is this, like, broad category, but there's probably multiple underlying things that are actually happening that are actually different forms of diabetes, for example.

Speaker 0

睡眠问题、失眠这些也是一样,肯定不止一种原因。

Probably same thing with, like, sleep, insomnia, all this kind of stuff.

Speaker 0

但要分辨这些差异,光靠普通检查根本不够,得有大量连续的数据,才能看出它跟健康状态到底有什么不同——这我觉得特别关键。

There's probably underlying multiple pathologies, but it's hard to tell that if unless you have a more massive stream of data that is coming that can help you tell, like, how that's changing and how that's changing from a healthy baseline, which I think is really important.

Speaker 0

对吧?

Right?

Speaker 0

今天我就戴着那个口腔环,作为一个健康人。

I am wearing the oral ring today as a healthy person.

Speaker 0

等我生病的时候,它就能捕捉到我从健康状态到生病状态之间的变化。

As I develop a disease, it's going to catch things that change from my healthy baseline to, like, being a sicker person.

Speaker 0

这些变化以及它们自然发展的过程——其实就是自然病程研究——特别重要。

And those changes and how that naturally progresses, like natural history study basically, is really important.

Speaker 0

我觉得如果我们有更多人戴这种设备,就能把这种方法用在更多疾病上。

And I think we probably can do that for more diseases if we had more people wearing this kind of stuff.

Speaker 0

所以

So

Speaker 1

这简直就是真实世界数据的终极梦想。

This is the real world data dream.

Speaker 1

没错。

It is.

Speaker 1

真的。

Really.

Speaker 0

这

This is

Speaker 1

这不就是我们所有人都想要的吗?

what we all wanted.

Speaker 0

对。

Yeah.

Speaker 0

我觉得问题在于,真实世界的数据一直以来更偏向于制药公司的应用场景。

And I think and I think the problem is real world data has always been focused a little bit more on like pharma use cases.

Speaker 0

我觉得还有很多普通人其实就想知道自己是不是有类似这种奇怪睡眠模式的人。

Think I there are a lot of people that are also just like, I kinda wanna know if there's other people like me who have this sort of weird sleep pattern.

Speaker 1

是的。

Yes.

Speaker 0

那他们都在做什么?

And what does that what are they doing?

Speaker 0

这说明了什么?

What does that mean?

Speaker 0

你知道吧?

You know?

Speaker 0

我觉得这是个特别开放、还没人深入探索的领域。如果有人在听的话,我觉得基于这些理念建立一个以患者为中心的生物样本库,真的很有意思。

That's I think a really open unexplored space that people have not quite, you know, I think if anyone is listening to this, I think building a patient first biobank on these concepts, think is really interesting.

Speaker 0

人们真的很想知道,那些和自己长相相似、生物标志物也类似的人,是怎么应对这种情况、怎么生活的。

People really do wanna know how people that look like them or have biomarkers that look like them, deal with that or operate in world.

Speaker 0

他们的治疗经历是怎样的?哪怕去掉了所有身份信息,这类数据也值得了解。

What does their care journey look like even if you de identify it or all this kind of stuff?

Speaker 0

知道有人和你一样有奇怪的睡眠模式,吃了某种剂量的镁,结果真的有效,这很有帮助。当我们细分人群时,你会发现他们和你特别像。

It's useful to know, hey, this person who had this weird sleep pattern took this magnesium dosage and it actually seemed to work for them and they actually, you know, when we sub cohort the populations, they look very similar to you.

Speaker 0

所以,也许你也该试试。

So maybe you should try it.

Speaker 0

对吧?

Right?

Speaker 1

是的。

Yeah.

Speaker 0

这确实还没人好好研究过。

That's very unexplored.

Speaker 0

我觉得可穿戴设备这些东西,正是实现这一点的好办法。

And I think wearables and all this kind of stuff is a way to do that.

Speaker 0

但前提是得有办法把这类数据系统化地收集起来,你说对吧?

But we can only do that if there is some, you know, way to capture that data in a structured way, basically, right?

Speaker 0

得找个折中的办法才能做到。

And you need a middle path to do that.

Speaker 1

这正好能引出我们接下来要聊的话题。

So that's a good transition to talk about.

Speaker 1

你之前提了大概三个关于医疗AI的预测。

You had three or so predictions around healthcare AI.

Speaker 1

第一个是关于州政府和联邦政府在关键监管上的冲突。

And your first one was around state governments clashing with the federal government on key regulations.

Speaker 1

你可以从几个角度聊聊,但咱们先聚焦在AI上。

Talk about it across a few dimensions, but let's zoom in on AI.

Speaker 1

州政府和联邦政府会在公共卫生指南、疫苗建议、AI监管、保险法细节这些方面产生分歧。

So state governments will clash with the federal government on public health guidelines, vaccine recommendations, AI regulation, insurance law nuances.

Speaker 1

以上所有。

All of the above.

Speaker 1

对,咱们聊聊这个。

Yeah, let's talk about that.

Speaker 1

说到AI,我觉得这个挺有意思的。

So on AI specifically, think this is interesting.

Speaker 1

去年,伊利诺伊州、内华达州,还有其他几个州,要么禁止,要么限制AI心理聊天机器人使用。

Last year, we had Illinois and Nevada and a couple other states either ban or restrict AI therapy chatbot usage.

Speaker 1

就在上周——你写那篇文章之后——犹他州刚启动了一个试点项目,允许AI开处方药。

Basically last week, so since you wrote your piece, we literally had Utah doing the pilot around AI being allowed to prescribe medications.

Speaker 1

目前范围很窄,只涉及190种低风险药物,比如哮喘吸入器这类。

It's very narrow on 190 low risk medications, your asthma inhaler, things like that.

Speaker 1

先从低风险的开始,以后再慢慢扩展。

Low risk stuff to start, but can expand.

Speaker 1

然后特朗普总统去年12月签了一项行政令,意思就是:我们要搞一个全国统一的框架,让大家更容易遵守。

And then President Trump signed an executive order in December saying, that effectively said, hey, we're gonna do a national framework and we'll make it easy for folks to follow.

Speaker 1

听起来你觉得2026年会更乱一些。

It sounds like you think it's gonna be more chaotic in 2026.

Speaker 1

肯定的。

Definitely.

Speaker 1

再多说说。

Say more.

Speaker 0

我的意思是,我觉得有好几方面吧。

I mean, I think it's I mean, I think there's a couple things.

Speaker 0

对吧?

Right?

Speaker 0

一方面,美国确实正在兴起一股反AI的潮流,这其实挺正常,大家担心失业,也担心那些影响自己生活的决定是由AI做的——比如,可能有个AI在背后做选择,结果反而对你不利。

One part is there is definitely an anti AI sort of movement that is happening in The US, which is sort of expected and natural, and people are worried about job loss, and they're worried about how decisions are being made that affect their lives because, like, maybe there's an AI on the other end that is choosing things that are, you know, anti helping them.

Speaker 0

对吧?

Right?

Speaker 0

所以我能理解这种反AI情绪,它迟早会影响政策。

So I understand, like, where that's coming from and that anti AI movement will inevitably impact policy.

Speaker 0

而且你待在哪个州,那个州的监管机构就会站在其中一方。

And depending on which state you're in, you're going to have a regulator in that state side with one side or the other.

Speaker 0

对吧?

Right?

Speaker 0

举个例子,就像Waymo那样。

Maybe like analog here is actually like Waymo's.

Speaker 0

对吧?

Right?

Speaker 0

Waymo现在只在几个州运营。

Waymo's are in a few states.

Speaker 0

最早是从加州开始的。

They started in California.

Speaker 0

我每次来这儿都超爱坐Waymo,真的特别棒。

They are super like I love riding in a Waymo every time I come here.

Speaker 0

各州对要不要让Waymo进来,看法差得可远了,对吧?

States have very different opinions on whether they should allow Waymo's into their own state, right?

Speaker 0

不管是他们担心得拿出多少证据来证明安全性才敢上线,还是知道一旦推广开来,会带来大规模的失业。

Whether it's they care about how much they have to prove safety wise before they roll out or they, you know, there's they know there's gonna be widespread job loss when they come in.

Speaker 0

我觉得其他领域的AI也会走同样的路。

And I think AI for other things is just gonna follow the same trend.

Speaker 0

对吧?

Right?

Speaker 0

所以问题在于,各州其实不太清楚该怎么下手。

And so I think the issue is that, like, states don't quite know what to do.

Speaker 0

我觉得咱们都明白,AI也存在不少滥用的情况,比如深度伪造啊、各种奇怪的用途,这些我们都得提防,对吧?

Like, I think we can all acknowledge that there's a lot of like also bad AI use cases that we need to watch out for using deepfakes and weird ways and a lot of this kind of stuff, right?

Speaker 0

所以总的来说,大家其实都在琢磨:怎么在控制AI潜在风险的同时,又不挡住它带来的巨大好处?

So as a whole, I think people are trying to figure out how do we regulate the downside risk of AI while also enabling the like upside potential that we can see, right?

Speaker 0

也许现在这样各州各自试点、看看哪些管用哪些不行,最后再搞出一个全国性的框架,反倒不是坏事。

And maybe it's actually not a bad thing that we're running a bunch of state by state experiments to see like what works and what doesn't and then create a more national framework to do this.

Speaker 0

不过 downside 是,就像医疗行业一样,每个州的合规要求都不一样,搞得产品得改来改去,进一个新州的成本也天差地别。

The downside though, is then you have to you know, healthcare has always been really annoying about having different compliance rules for every state, which means your product looks very different and the cost to go in a new state is very different.

Speaker 0

这确实挺麻烦的,但也许我们真该在各地试试不同的办法。

That's gonna be annoying, but actually, maybe we should be running different experiments here.

Speaker 0

每个州都会不一样,毕竟各自的医疗需求也不同。

And each state is gonna, you know, it's gonna look different depending on their own health care needs as a state.

Speaker 0

对吧?

Right?

Speaker 0

比如你这儿农村人口多,看病特别难,那肯定得赶紧想办法,让这些人至少有个家庭医生。

If you have a really large rural population, for example, that really struggles to get access to care, you're probably gonna lean more heavily into, hey, we need to get these people don't have a PCP.

Speaker 0

得给他们点实际的帮助。

We need to get them something.

Speaker 0

对吧?

Right?

Speaker 0

要是你这儿医疗资源竞争激烈,那情况可能就不同了,看病方便得很,根本不用操心。

If you have a very competitive provider network, maybe that's actually not the case, and care accessibility is fine and all that.

Speaker 0

所以我觉得,各州其实都在琢磨:怎么在控制风险的同时抓住机会,但问题是,大家对这事儿的理解根本不一样。

So I think that'll I think it just really I think that states are trying to figure out like how do we protect the downsides while getting the upsides, but they just don't they all have a different opinion on what that means.

Speaker 0

比如有些州,他们就是不希望保险公司用AI来拒赔。

Like some states, for example, you know, they really don't want insurance companies to use AI to deny claims.

Speaker 0

对吧?

Right?

Speaker 0

他们觉得这事儿特别糟糕,诸如此类的。

They're like, they think that's like really bad, blah blah blah.

Speaker 1

他们反而更愿意让人来拒赔。

They'd rather have humans deny this.

Speaker 0

没错。

Yeah.

Speaker 0

可问题是,他们怎么去监管呢?

Which which also at the same time, almost like, how are they even gonna monitor?

Speaker 0

要是人用ChatGPT来判断理赔然后拒掉,这跟用AI有啥区别?

If a human is using ChatGPT Yeah.

Speaker 0

说到底,真的不一样吗?

To lead the claim and then deny it, is it really any different?

Speaker 0

是啊,当然。

Yeah, sure.

Speaker 0

我不是特别确定,说实话我也不清楚。

Not to be clear, but I don't know.

Speaker 0

咱们走着瞧吧。

We'll see.

Speaker 0

肯定会有些州搞出些有趣的实验来。

It'll be some fun, fun state experiments.

Speaker 1

对,我觉得你说得对。

Yeah, I think that's right.

Speaker 1

从竞争力的角度,还有为了让所有创新想法都能冒出来——毕竟最终受益的是消费者——我觉得必须得有个全国统一的框架。

I think from a competitiveness standpoint and from getting all the innovative ideas out there, which ultimately benefits the consumer, I think you've got to have a national framework.

Speaker 1

没错。

Sure.

Speaker 1

因为如果每个州都有不同的监管规则,搞得特别复杂,那只会让现有大公司占便宜,他们有庞大的法律团队,能搞懂所有规定,还能据此运营和扩张。

Because if you have a lot of regulatory complexity with different rules in every states, it favors the incumbents who have the armies of legal teams that can interpret all those things and operationalize and scale in that way.

Speaker 1

你想让大科技和小科技站在同一条起跑线上。

You want to level the playing field for big tech and little tech.

Speaker 1

但另一方面,你也希望有实验的空间。

On the other hand, you want the experimentation.

Speaker 1

我觉得当技术发展这么快的时候,你希望监管能跟上,但你根本不知道什么才是正确的做法。

I think when the technology is moving so fast, you want regulation to catch up, but you really don't know what the right answer is.

Speaker 1

所以像你所说的,让不同州根据各自的人口结构和城乡分布来试点,确实很有启发性。

And so it's instructive to have different states experiment for their unique population mix and rural to urban mix as you described.

Speaker 1

所以对我来说,关键问题是:我们有没有足够的数据基础设施,能从这些实验中学到东西?

And so I think the question for me is do we have the right data infrastructure to learn from all that stuff?

Speaker 1

比如处方药这个例子就挺有意思的。

So like the prescription example is an interesting one.

Speaker 1

好,明白了。

Okay, great.

Speaker 1

你知道的,处方药续药,4美元就能搞定,不用花150美元。

You know, you can refill a prescription for $4 instead of $150 Sure.

Speaker 1

咱们看看这招管不管用,好处和坏处分别是什么。

Let's see if that works and let's see the upsides and downsides of it.

Speaker 1

从这个州的试点项目里,咱们能学到不少东西。

We're going to learn a lot from that state pilot.

Speaker 1

没错。

Sure.

Speaker 1

但这只是其中一个例子。

But that's just one example.

Speaker 1

咱们得让五十个不同的例子都试试看。

We want 50 different examples to play out.

Speaker 1

这正是我担心的地方。

And that's the thing that I worry about.

Speaker 0

是的。

Yeah.

Speaker 0

我的意思是,如果我们

I mean, you know If we

Speaker 1

就等国家层面吧。

wait just for National, basically.

Speaker 0

对。

Yeah.

Speaker 0

我的意思是,其实也有种观点认为,我记得乔纳森·斯洛特金写过一篇特别棒的评论,说Waymo的技术已经好到某种程度,要是到处推广反而不道德了。

I mean, there's an argument to be made also that I I thought actually that I think Jonathan Slotkin wrote like a great op ed about Waymo's seem to have proven that, like, they're so good that actually would be unethical Yes.

Speaker 0

不该全面铺开。

Not roll it out everywhere.

Speaker 1

太厉害了。

So good.

Speaker 0

对吧?

Right?

Speaker 0

我觉得如果我们能这么做就好了:这个试点项目效果这么好,我们就该赶紧推广到全国各地。

And I think if you can if we can do something around the in the lines of, hey, this pilot or this thing looks so good, we really just gotta boost it everywhere.

Speaker 0

对。

Yeah.

Speaker 0

我觉得联邦政府其实可以换种思路,别一上来就搞一刀切的规矩。

I think that can actually be maybe a different way the federal government thinks about things rather than be like, hey, we're gonna set blanket rules.

Speaker 0

对。

Yeah.

Speaker 0

不如让各地自己先试自己的方案。

It can be like, all these places should test their own things out.

Speaker 0

要是哪个地方的效果真不错,那就……

If something looks like it's working Yes.

Speaker 0

把它的做法推广到全国。

Then we make that the rule for everyone else.

Speaker 0

然后赶紧把那些功能或项目推给所有人。

And then like, speed run getting people getting those getting that whatever, getting those features or programs out to everybody.

Speaker 1

没错。

Yes.

Speaker 0

别老想着先搞个‘这玩意儿行得通’的官方认证。

Rather than be like, hey, we need to create a yes, it's working.

Speaker 0

不用上来就规定死

No, it's working.

Speaker 0

给所有州统一套一套规则

Rule set for every state.

Speaker 0

对

Yeah.

Speaker 0

不如就让各州自己先试点测试,管用了再全国推广

Just be like, go run your own pilots and tests and then let's get it up.

Speaker 1

《纽约时报》那篇讲Waymo的文章,对,没错

The New York Times article around Waymo Yeah.

Speaker 1

就是个绝佳的例子

Is a perfect example.

Speaker 1

而且有意思的是,文章里提到医疗健康和生命科学行业早就有这套逻辑了:如果你在做临床试验,期间疗效已经明明白白摆在那了,再继续试验就不符合伦理了——因为你还给对照组用安慰剂,这会坑到他们的

And actually, ironically, it it pointed to healthcare and life sciences as an industry that already has this framework, which is if you're running a clinical trial and the evidence is as clear as day, at some point it becomes unethical to continue the trial because you're giving the placebo to the control arm and it's causing them.

Speaker 1

你懂的,就是会害到那群人

And you know it's them.

Speaker 1

那这里到底是什么样的框架呢?

And so what is the framework like that here?

Speaker 1

我觉得这个值得重点关注。

I think this is going to be one to watch.

Speaker 1

这跟医疗AI领域的知识产权争议密切相关。

That relates to IP and all the IP debates around HealthCare AI.

Speaker 0

对。

Yeah.

Speaker 1

没错。

Yeah.

Speaker 1

你说过,医疗AI领域的知识产权界限会逐渐明确,会出现丰厚的版权和授权交易。

So you said intellectual property lines will be drawn in HealthCare AI with lucrative copyright and licensing deals.

Speaker 1

没错。

Yeah.

Speaker 1

这张照片,我们一会儿放出来给大伙儿看看,画的是大鸟把你勒得喘不过气。

This photo, which we'll put it up for the people out there with big birds strangling you.

Speaker 0

你知道吗,有时候我老婆闯进来,看到我正在工作,这次她看见我输出了一张埃尔莫把我勒住的图。

Know, sometimes my wife walks in on me doing my work, and in this case, she's seeing me, like, output an image of Elmo choking me out.

Speaker 0

她还问,这真的就是我们家的饭钱来源?

And she's this is, like, really what's putting food on the table.

Speaker 1

没错。

Exactly.

Speaker 1

她都在怀疑你到底有没有正经工作。

She's wondering if you have a real job.

Speaker 1

是啊。

Yeah.

Speaker 1

对啊。

Yeah.

Speaker 1

所以说,这事儿真是疯了。

So so, I mean but it's crazy.

Speaker 1

那你给大家说说,AI整体上到底是怎么回事。

So so lay that out, lay out that case for AI overall.

Speaker 1

当然。

Sure.

Speaker 1

那些纷繁的版权纠纷和诉讼都闹得沸沸扬扬,那在医疗领域具体会是什么情况?

All the drama deals and litigations that And happened last then what does it look like in healthcare specifically?

Speaker 0

我的意思是,从基础模型的角度来看,最大的问题一直是:当AI服务在复述、输出内容,或者以从未被允许的方式使用知识产权时,版权到底该怎么界定?

Yeah, mean, the foundation model side, the big issue has always been like, does copyright look like in an era where, you know, the AI service regurgitating or spitting out things or like using IP in ways it was never supposed to be.

Speaker 0

这就跟埃尔莫勒死我一样。

It's like Elmo choking me out.

Speaker 0

对吧?

Right?

Speaker 0

没错。

Yeah.

Speaker 0

现在呢,一堆诉讼和合作同时在发生,不同的基础模型被允许使用各大公司的知识产权。

And now there's a bunch of lawsuits slash partnerships that have been happening where different foundation models now are allowed to use the IP from different companies.

Speaker 0

我觉得迪士尼投资了OpenAI。

So I think Disney invested in OpenAI.

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